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Rudolf Uher Selected Research

Nortriptyline (Aventyl)

1/2019Effect of antidepressant switching between nortriptyline and escitalopram after a failed first antidepressant treatment among patients with major depressive disorder.
1/2019Trajectories of Suicidal Ideation During 12 Weeks of Escitalopram or Nortriptyline Antidepressant Treatment Among 811 Patients With Major Depressive Disorder.
10/2018Genetic disposition to inflammation and response to antidepressants in major depressive disorder.
1/2016Combining clinical variables to optimize prediction of antidepressant treatment outcomes.
12/2014An inflammatory biomarker as a differential predictor of outcome of depression treatment with escitalopram and nortriptyline.
2/2013Candidate genes expression profile associated with antidepressants response in the GENDEP study: differentiating between baseline 'predictors' and longitudinal 'targets'.
12/2012Self-report and clinician-rated measures of depression severity: can one replace the other?
11/2012Antidepressant-dependent mRNA changes in mouse associated with hippocampal neurogenesis in a mouse model of depression.
10/2012Non-random dropout and the relative efficacy of escitalopram and nortriptyline in treating major depressive disorder.
4/2011Changes in body weight during pharmacological treatment of depression.
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Rudolf Uher Research Topics

Disease

37Major Depressive Disorder (Major Depressive Disorders)
04/2022 - 11/2009
10Bipolar Disorder (Manic Depressive Psychosis)
01/2022 - 04/2006
9Depressive Disorder (Melancholia)
01/2019 - 03/2009
7Obesity
07/2019 - 11/2009
6Schizophrenia (Dementia Praecox)
04/2022 - 05/2014
6Genetic Risk Score
01/2019 - 01/2014
5Psychotic Disorders (Schizoaffective Disorder)
12/2020 - 01/2014
5Inflammation (Inflammations)
10/2018 - 02/2013
3Drug-Related Side Effects and Adverse Reactions
11/2021 - 09/2009
3Anhedonia
01/2020 - 01/2018
3Mental Disorders (Mental Disorder)
01/2020 - 01/2016
3Weight Gain
07/2011 - 09/2009
2Treatment-Resistant Depressive Disorder
01/2021 - 01/2019
2Mood Disorders (Mood Disorder)
01/2020 - 06/2019
2Overweight
01/2018 - 11/2009
2Pain (Aches)
01/2017 - 01/2009
2Insulin Resistance
01/2015 - 11/2014
2Sleep Initiation and Maintenance Disorders (Insomnia)
07/2011 - 09/2009
2Body Weight (Weight, Body)
04/2011 - 11/2009
2Neurobehavioral Manifestations
12/2010 - 03/2009
1Morbid Obesity
10/2021
1Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
01/2021
1Syndrome (Syndromes)
01/2020
1Dementia (Dementias)
12/2019
1Postpartum Depression (Post-Natal Depression)
01/2019
1Autism Spectrum Disorder
01/2018
1Dyslipidemias (Dyslipidemia)
01/2018
1Intellectual Disability (Idiocy)
10/2017
1Growth Disorders
01/2017
1Dizziness (Lightheadedness)
07/2015
1Type 2 Diabetes Mellitus (MODY)
01/2015
1Atrophy
11/2014
1Glucose Intolerance
11/2014
1Genetic Predisposition to Disease (Genetic Predisposition)
01/2014
1Huntington Disease (Huntington's Disease)
11/2012
1Weight Loss (Weight Reduction)
04/2011
1Feeding and Eating Disorders (Eating Disorder)
04/2010
1Bulimia (Binge Eating)
04/2010
1Constipation
09/2009
1Bulimia Nervosa
01/2009
1Hallucinations (Hallucination)
04/2006

Drug/Important Bio-Agent (IBA)

35Antidepressive Agents (Antidepressants)IBA
04/2022 - 09/2009
20EscitalopramFDA Link
01/2020 - 03/2009
17Nortriptyline (Aventyl)FDA LinkGeneric
01/2019 - 03/2009
9Biomarkers (Surrogate Marker)IBA
01/2022 - 12/2014
7Biological ProductsIBA
01/2022 - 01/2017
5Pharmaceutical PreparationsIBA
11/2021 - 07/2011
4LithiumIBA
11/2021 - 12/2012
4Proteins (Proteins, Gene)FDA Link
07/2019 - 01/2018
3C-Reactive ProteinIBA
10/2018 - 12/2014
3Messenger RNA (mRNA)IBA
05/2014 - 02/2013
3Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2014 - 09/2010
3CytokinesIBA
09/2013 - 02/2013
2Aripiprazole (Abilify)FDA Link
01/2020 - 01/2019
2Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
01/2019 - 12/2014
2Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA
01/2019 - 04/2011
2Glucose (Dextrose)FDA LinkGeneric
01/2015 - 11/2014
2Norepinephrine (Noradrenaline)FDA LinkGeneric
12/2014 - 01/2012
2Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA
01/2014 - 02/2013
1cyclo(Arg-Pro) (CI 4)IBA
01/2021
1HLA Antigens (Human Leukocyte Antigens)IBA
01/2020
1Indicators and Reagents (Reagents)IBA
01/2020
1Complement C4 (Complement Component 4)IBA
01/2020
1ProgesteroneFDA LinkGeneric
01/2019
1Testosterone (Sustanon)FDA Link
01/2019
1Duloxetine Hydrochloride (Cymbalta)FDA Link
01/2019
1Estradiol (Delestrogen)FDA LinkGeneric
01/2019
1Hormones (Hormone)IBA
01/2019
1Tuberculin (PPD)IBA
01/2019
1ProlactinIBA
01/2019
1Polytetrafluoroethylene (Teflon)FDA Link
01/2018
1Folic Acid (Vitamin M)FDA LinkGeneric
01/2018
1Proteoglycans (Proteoglycan)IBA
01/2017
1GlycosaminoglycansIBA
01/2017
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
01/2017
1Insulin (Novolin)FDA Link
01/2015
1Vesicle-Associated Membrane Protein 2 (VAMP2)IBA
05/2014
1CitalopramFDA LinkGeneric
09/2013
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
02/2013
1Tacrolimus Binding Proteins (FKBP)IBA
02/2013
1InterleukinsIBA
02/2013
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2013
1IntegrinsIBA
11/2012
1Serotonin (5 Hydroxytryptamine)IBA
01/2012
1salicylhydroxamic acid (SHAM)IBA
04/2010
1Lamotrigine (Lamictal)FDA LinkGeneric
04/2006

Therapy/Procedure

3Therapeutics
01/2019 - 05/2017
1Precision Medicine
01/2019
1Drug Therapy (Chemotherapy)
10/2013
1Transcranial Magnetic Stimulation
04/2010
1Analgesia
01/2009